Company Filing History:
Years Active: 2019-2023
Title: The Innovations of Daniel Ramsay Higazi
Introduction
Daniel Ramsay Higazi is a notable inventor based in Cambridge, GB. He has made significant contributions to the field of biotechnology, particularly in the development of recombinant polypeptide therapeutics. With a total of 3 patents to his name, Higazi's work has the potential to impact various therapeutic applications.
Latest Patents
Higazi's latest patents include "Engineered O-glycosylation in recombinant polypeptides and uses thereof." This invention relates to recombinant polypeptide therapeutics that feature an engineered O-linked amino acid glycosylation sequence, which is covalently linked to O-glycans. These polypeptides can be produced in mammalian cells, allowing for the presentation of both natural and unnatural O-glycan structures through metabolic labeling. Another significant patent is "Prevention of N-terminal truncation in IgG light chains." This discovery addresses the issue of recombinant antibody light chains being truncated during post-translational processing. Higazi provides two effective protein engineering solutions to prevent this truncation, showcasing his innovative approach to biotechnology.
Career Highlights
Higazi is currently employed at Medimmune Limited, where he continues to advance his research and development efforts. His work at Medimmune has positioned him as a key player in the field of therapeutic innovations.
Collaborations
Higazi collaborates with talented colleagues, including Adam Tibbles and Monika Anna Papworth. These collaborations enhance the research environment and contribute to the success of their projects.
Conclusion
Daniel Ramsay Higazi's contributions to biotechnology through his patents and work at Medimmune Limited highlight his innovative spirit and dedication to advancing therapeutic solutions. His research continues to pave the way for future developments in the field.