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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11834473 B1

PDFFull Text
Date of Patent:
Dec. 05, 2023

Filed:

Dec. 20, 2018

Engineered o-glycosylation in recombinant polypeptides and uses thereof

Applicant:

Medimmune Limited, Cambridge, GB;

Inventors:

Adam Tibbles, Cambridge, GB;

Monika Papworth, Cambridge, GB;

Daniel Higazi, Cambridge, GB;

Emmanuel Rossy, Cambridge, GB;

Katarzyna Anna Kozakowska, Cambridge, GB;

Thomas Vincent Murray, Cambridge, GB;

Assignee:

MedImmune Limited, Cambridge, GB;

Attorney:
Primary Examiner:

Tekchand Saidha

Int. Cl.
CPC ...
A61K 47/62 (2017.01); C07K 1/107 (2006.01); C07K 9/00 (2006.01); C07K 14/605 (2006.01); C12P 21/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 1/1077 (2013.01); A61K 47/62 (2017.08); C07K 9/001 (2013.01); C07K 14/605 (2013.01); C12P 21/005 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01);
Abstract

The present invention relates to recombinant polypeptide therapeutics having an engineered O-linked amino acid (AA) glycosylation sequence (motif), which is covalently linked to O-glycan(s) (tag). Recombinant O-glycosylated polypeptides may be produced in mammalian cells to present natural or un-natural O-glycan structures through metabolic labelling.

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Tibbles, Adam. (2023). Engineered o-glycosylation in recombinant polypeptides and uses thereof (U.S. Patent No. 11834473). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11834473

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