Craig Ostrander

Title: Craig Ostrander: Innovator in DNA Polymerase Variants

Introduction

Craig Ostrander is a notable inventor based in Bothell, WA (US), recognized for his contributions to the field of biotechnology. He holds a total of four patents, showcasing his innovative work in DNA polymerase variants.

Latest Patents

Ostrander's latest patents include the development of recombinant DPO4-type DNA polymerase variants. These variants feature amino acid substitutions that enhance the polymerase's properties for improved single molecule sequencing applications. The modifications allow for better binding and incorporation of bulky nucleotide analog substrates into daughter strands. Additionally, the patents provide compositions that include these DPO4 variants and nucleotide analogs, as well as nucleic acids encoding the polymerases with the desired phenotypes.

Career Highlights

Throughout his career, Craig Ostrander has worked with prominent companies in the biotechnology sector, including Stratos Genomics, Inc. and Zymogenetics, Inc. His work has significantly advanced the understanding and application of DNA polymerases in sequencing technologies.

Collaborations

Ostrander has collaborated with notable professionals in his field, including Mark Stamatios Kokoris and Marc Prindle. These collaborations have contributed to the development of innovative solutions in DNA sequencing.

Conclusion

Craig Ostrander's work in developing DPO4 polymerase variants has made a significant impact on the field of biotechnology. His innovative contributions continue to influence advancements in single molecule sequencing applications.