Location History:
- Madison, WI (US) (2012)
- Los Angeles, CA (US) (2012 - 2023)
- Pacific Palisades, CA (US) (2019 - 2024)
Company Filing History:
19 out of 597 
7 out of 77 
3 out of 4,125 
Years Active: 2012-2025
Title: Clive N. Svendsen: Advancing Neurodegenerative Disease Modeling
Introduction
Clive N. Svendsen, based in Pacific Palisades, California, is a prominent inventor known for his groundbreaking contributions to the field of neurodegenerative disease research. With an impressive portfolio of 22 patents, Svendsen's innovations are at the forefront of utilizing human pluripotent stem cells and microfluidic technology to develop effective models for studying diseases such as Parkinson's Disease.
Latest Patents
Among his latest patents, Svendsen has focused on the development of human pluripotent stem cell-derived neurodegenerative disease models on a microfluidic chip. This microphysiological system leverages induced pluripotent stem cells (iPSCs) to create models that accurately reflect the pathology of diseases. Specifically, his work on Parkinson's Disease has yielded a vascularized human model containing neurons that exhibit key pathology associated with the disease. These innovations facilitate the analysis of biomarkers, patient screening, and therapeutic discovery. Additionally, he has developed a spinal cord on a microfluidic chip, enhancing the maturation and differentiation of brain endothelial cells and other neuronal cells to better mimic the blood-brain barrier.
Career Highlights
Clive N. Svendsen's career spans significant affiliations with notable institutions including Cedars-Sinai Medical Center and Emulate, Inc. His work consistently emphasizes the importance of utilizing advanced technologies to understand and treat neurodegenerative diseases, ultimately contributing to better patient outcomes through research and innovation.
Collaborations
Throughout his career, Svendsen has collaborated with prominent colleagues, including Dhruv Sareen and Norman Wen. These partnerships have fostered a collaborative environment that encourages innovation and accelerates the pace of research in the field of neurodegenerative diseases.
Conclusion
Clive N. Svendsen's innovative approach to neurodegenerative disease modeling through the use of microfluidic technology and human stem cells positions him as a key figure in medical research. His numerous patents and collaborations underline his commitment to advancing our understanding of diseases like Parkinson's, paving the way for future therapies and improved patient care.