The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2026
Filed:
Sep. 22, 2021
Applicant:
Cedars-sinai Medical Center, Los Angeles, CA (US);
Inventors:
Samuel Sances, Santa Monica, CA (US);
Clive Svendsen, Pacific Palisades, CA (US);
Assignee:
Cedars-Sinai Medical Center, Los Angeles, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); B01L 3/00 (2006.01); C12M 3/00 (2006.01); C12N 5/0793 (2010.01);
U.S. Cl.
CPC ...
G01N 33/5058 (2013.01); B01L 3/502715 (2013.01); C12M 21/08 (2013.01); C12N 5/0619 (2013.01); G01N 33/5023 (2013.01); B01L 2300/0874 (2013.01); C12N 2501/01 (2013.01); C12N 2501/13 (2013.01); C12N 2503/02 (2013.01); C12N 2506/45 (2013.01); C12N 2513/00 (2013.01); C12N 2533/52 (2013.01); C12N 2533/54 (2013.01); C12N 2533/90 (2013.01);
Abstract
Described herein are the effects of continuous media perfusion on SC-Chips and the observed activation of pronounced neural tissue growth and vascular recruitment into the neural tissue channel. ALS patient chip overexpression of known neurodegenerative disease biomarkers neurogranin and neurofilament family members are also described and utilized for the invention.