Samuel Sances

Title: Innovations of Samuel Sances

Introduction

Samuel Sances is an accomplished inventor based in Santa Monica, California. He holds a total of six patents, showcasing his significant contributions to the field of biomedical engineering. His work primarily focuses on developing innovative models for studying neurodegenerative diseases and the blood-brain barrier.

Latest Patents

One of his latest patents is the "Microfluidic model of the blood brain barrier." This invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons, in a fluidic device. The conditions within this device allow the cells to mimic the structure and function of the blood-brain barrier. This culture method drives maturation and differentiation further than existing systems. Another notable patent is the "Human pluripotent stem cell derived neurodegenerative disease models on a microfluidic chip." This microphysiological system utilizes induced pluripotent stem cells (iPSCs) and iPSC-derived cells to study cellular development and disease pathogenesis. It specifically addresses neurodegenerative diseases, including Parkinson's Disease, by reproducing key pathology in a vascularized human model.

Career Highlights

Samuel has worked with prestigious organizations such as Cedars-Sinai Medical Center and Emulate, Inc. His experience in these institutions has allowed him to advance his research and contribute to significant innovations in the field.

Collaborations

Some of his notable coworkers include Clive N Svendsen and Gad Vatine. Their collaborative efforts have further enhanced the impact of his research and inventions.

Conclusion

Samuel Sances is a pioneering inventor whose work in microfluidic systems and neurodegenerative disease modeling is making a substantial impact in biomedical research. His innovative patents and collaborations continue to push the boundaries of scientific understanding and therapeutic development.