Location History:
- Rockport, MA (US) (1997)
- Boxford, MA (US) (1998 - 2015)
Company Filing History:
Years Active: 1997-2015
Title: The Innovations of Christopher J Noren
Introduction
Christopher J Noren is a notable inventor based in Rockport, MA (US). He has made significant contributions to the field of molecular biology, particularly in the detection and quantification of nucleotides. With a total of 8 patents to his name, Noren's work has advanced our understanding of gene expression and gene silencing.
Latest Patents
One of Noren's latest patents focuses on the detection and quantification of hydroxymethylated nucleotides in a polynucleotide preparation. This patent describes methods and compositions for detecting hydroxymethylated nucleotides (hmNs) in a genome. The goal is to map the location of hmNs, quantify their occurrence at selected loci, and correlate this occurrence with gene expression and phenotypic traits. The embodiments of this patent utilize modifying enzymes alongside site-specific endonucleases to effectively detect hmNs.
Another significant patent relates to gene silencing. This method involves obtaining a mixture of heterogeneous short double-stranded RNA molecules suitable for gene silencing (hsiRNA) by enzymatically cleaving large double-stranded RNA under specific conditions. The resulting mixture consistently includes fragments sized 21-22 nucleotides, which span the entire length of the original RNA. This method allows for the analysis of double-stranded RNA sequences to identify the most active subsets of hsiRNA fragments for effective gene silencing.
Career Highlights
Christopher J Noren is currently employed at New England Biolabs, Inc., where he continues to innovate in the field of molecular biology. His work has been instrumental in developing new techniques that enhance our understanding of genetic mechanisms.
Collaborations
Noren has collaborated with notable colleagues, including Richard J Roberts and Devon R Byrd. These collaborations have further enriched his research and contributed to the advancement of molecular biology.
Conclusion
Christopher J Noren's contributions to the field of molecular biology through his patents and innovative methods have made a significant impact. His work continues to influence research in gene expression and silencing, showcasing the importance of innovation in science.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.