Location History:
- Bethesda, MD (US) (2014)
- Silver Spring, MD (US) (2011 - 2021)
Company Filing History:
13 out of 3,539 
1 out of 1 
1 out of 8,686 
Years Active: 2011-2021
Title: **Innovative Contributions of Che-Hung Robert Lee**
Introduction
Che-Hung Robert Lee, an accomplished inventor based in Silver Spring, MD, is recognized for his significant contributions to the field of immunology and vaccine development. With a remarkable portfolio of 13 patents, his work primarily focuses on enhancing the efficacy of meningococcal vaccines through innovative formulations.
Latest Patents
Lee's latest patents showcase cutting-edge advancements in immunogenic compositions. One notable patent is for "Bacterial polysaccharide-conjugated carrier proteins and use thereof," which describes immunogenic compositions featuring a bacterial capsular polysaccharide linked to a carrier protein. This work highlights the use of factor H binding protein (fHbp) linked to cholera toxin subunit B (CTB), aiming to elicit an immune response that promotes the production of specific antibodies against meningococcal polysaccharides.
Another significant patent, titled "Multivalent meningococcal conjugates and methods for preparing conjugates," focuses on improving immune responses against various meningococcal serogroups. The disclosed methods involve the activation of polysaccharides with a cyanylation agent, which plays a critical role in developing effective immunogenic conjugates exhibiting bactericidal activity against several serogroups, including A, C, W-135, Y, B, and X.
Career Highlights
Throughout his career, Che-Hung Robert Lee has made substantial contributions to public health through his innovative research. He has worked with esteemed organizations, including the United States Department of Health and Human Services, where his efforts have significantly advanced vaccine technology and effectiveness.
Collaborations
Lee’s collaborative spirit is evident in his work alongside notable colleagues such as Carl E. Frasch and Ellen Jessouroun. These partnerships have further enriched his research initiatives and helped drive important innovations in the field of immunology.
Conclusion
Che-Hung Robert Lee exemplifies the impact that dedicated inventors can have on public health through innovation and research. His extensive patent portfolio and collaborative work continue to pave the way for new advancements in vaccine development, underscoring his vital role in safeguarding global health.