This inventor holds 19 USPTO granted patents. Top assignees: Massachusetts Institute of Technology, University of Iowa Research Foundation, Children's Medical Center Corporation. Active years: 1982-2010.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
18 out of 8,586 
4 out of 925 
1 out of 1,073 
Years Active: 1982-2010
Title: Insights into the Innovations of Charles L. Cooney
Introduction
Charles L. Cooney, based in Brookline, MA, has made significant contributions in the field of biotechnology through his groundbreaking inventions. With a total of 19 patents to his name, his work primarily focuses on the purification and characterization of essential enzymes, particularly heparinases derived from Flavobacterium heparinum.
Latest Patents
Among his latest patents are "Purification, composition and specificity of Heparinase I, II, and III from Flavobacterium heparinum" and "Purification of Heparinase I, II and III from Flavobacterium heparinum." The first patent discloses a single, reproducible scheme to simultaneously purify all three heparin lyases from Flavobacterium heparinum to apparent homogeneity. It highlights the kinetic properties of the heparin lyases while also establishing the optimal conditions for their activity and stability. The patent also describes the development of mono-clonal antibodies that are invaluable for the detection, isolation, and characterization of these heparinases. The second patent details the production of purified Heparinase I, II, and III, which are free of lyase activity, exhibiting molecular weights of 42,800, 84,100, and 70,800, respectively.
Career Highlights
Charles has collaborated with prestigious institutions such as the Massachusetts Institute of Technology and the University of Iowa Research Foundation throughout his career. His innovative work has paved the way for advancements in the understanding and application of heparinases, driving forward research in biotechnology.
Collaborations
Cooney has teamed up with notable colleagues, including Robert J. Linhardt and Ramnath Sasisekharan, to further explore the complexities of enzymatic functions and their implications in various biomedical applications. These collaborations have proved instrumental in augmenting the impact of his research on the scientific community.
Conclusion
In summary, Charles L. Cooney remains a prominent figure in the field of biotechnology, with a diverse portfolio of patents that emphasize the purification and characterization of heparinases. His contributions not only reflect his innovative spirit but also showcase the importance of collaborations in driving scientific advancements. Through his work, he continues to inspire future research and innovation in the biotechnology sector.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile