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For the Inventor, By the Inventor

Stanford, CA, United States of America

Calvin F Quate

This inventor holds 75 USPTO granted patents, plus 1 CIPO patent, primarily in Atomic Force Microscopy (CPC class 3103). Top assignees: Leland Stanford Junior University, Xerox Corporation, Affymetrix, Inc.. Active years: 1976-2011.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Calvin F Quate. Retrieved from https://idiyas.com/inventor/calvin-f-quate

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 75

% Patents Active = 88.0


Average Co-Inventor Count = 2.1

ph-index = 32

Forward Citations = 2,713(Granted Patents)

Forward Citations (Not Self Cited) = 2,591(Dec 10, 2025)


Inventors with similar research interests:


Location History:

  • Los Altos Hills, CA (US) (1976 - 1977)
  • Los Altos Hill, CA (US) (1977)
  • Palo Alto, CA (US) (1986)
  • Stanford, CT (US) (1987)
  • Stamford, CA (US) (1993)
  • Stanford, CA (US) (1981 - 2003)
  • Menlo Park, CA (US) (2004 - 2011)

Company Filing History:

goldMedal43 out of 5,512 
 
Leland Stanford Junior University
 patents
silverMedal27 out of 24,259 
 
Xerox Corporation
 patents
bronzeMedal4 out of 561 
 
Affymetrix, Inc.
 patents
4. 1 out of 834,513 
Other
 patents

Years Active: 1976-2011

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Areas of Expertise:
Atomic Force Microscopy
Harmonic Cantilevers
Chemical Micromachined Microsensors
DNA Sequencing
Data Storage
Optical Lithography
Nanotube Fabrication
Photothermal Spectroscopy
Scanning Probe Microscope
Acoustic Lens
Ejection Units
Photolithography
75 patents (USPTO):Explore Patents
1. 8067169 - Detection of macromolecular complexes on ultraflat surfaces with harmonic cantilevers (2011-11-29),
2. 7989164 - Detection of macromolecular complexes with harmonic cantilevers (2011-08-02),
3. 7451638 - Harmonic cantilevers and imaging methods for atomic force microscopy (2008-11-18),
4. 7404314 - Atomic force microscope using a torsional harmonic cantilever (2008-07-29),
5. 7305883 - Chemical micromachined microsensors (2007-12-11),
6. 7302833 - Torsional harmonic cantilevers for detection of high frequency force components in atomic force microscopy (2007-12-04),
7. 7089787 - Torsional harmonic cantilevers for detection of high frequency force components in atomic force microscopy (2006-08-15),
8. 6935167 - Harmonic cantilevers and imaging methods for atomic force microscopy (2005-08-30),
9. 6770472 - Direct DNA sequencing with a transcription protein and a nanometer scale electrometer (2004-08-03),
10. 6519221 - High-density data storage using atomic force microscope (2003-02-11),
11. 6480324 - Methods involving direct write optical lithography (2002-11-12),
12. 6441359 - Near field optical scanning system employing microfabricated solid immersion lens (2002-08-27),
13. 6436647 - Method for detecting chemical interactions between naturally occurring biological analyte molecules that are non-identical binding partners (2002-08-20),
14. 6401526 - Carbon nanotubes and methods of fabrication thereof using a liquid phase catalyst precursor (2002-06-11),
15. 6346189 - Carbon nanotube structures made using catalyst islands (2002-02-12),

Title: Calvin F. Quate: Pioneering Innovations in Macromolecular Detection

Introduction

Calvin F. Quate is a renowned inventor and researcher based in Stanford, California. With a remarkable portfolio of 75 patents, his contributions have significantly advanced the field of atomic force microscopy and macromolecular detection methods. Quate's innovative approaches have paved the way for novel scientific discoveries and practical applications in molecular biology.

Latest Patents

Among Quate's latest patents are groundbreaking methods for detecting macromolecular complexes on ultraflat surfaces using harmonic cantilevers. His patents detail a method and apparatus that utilizes these cantilevers to measure variations in attractive and repulsive forces due to macromolecular binding, exemplified by the hybridization of single-stranded DNA molecules. The unique properties of complexed macromolecules, such as decreased flexibility and increased negative charge from amino acids or DNA monomers, are pivotal in this detection process. The patents emphasize the use of ultraflat surfaces, including gold-coated mica substrates, to enhance the precision of macromolecule deposition and detection.

Career Highlights

Calvin F. Quate has had an illustrious career, contributing his expertise to prestigious institutions including Leland Stanford Junior University and Xerox Corporation. His work has not only enriched academic circles but has also strengthened industry practices in molecular analysis and detection.

Collaborations

Throughout his career, Quate has collaborated with notable colleagues, including Butrus Thomas Khuri-Yakub and Stephen C. Minne. These collaborations have further propelled his innovative efforts in advancing atomic force microscopy and its applications in various scientific fields.

Conclusion

Calvin F. Quate's contributions to the realm of macromolecular detection represent a significant leap forward in scientific methodology. Through his 75 patents, he has established a legacy of innovation that continues to inspire future generations of inventors and researchers in the field of molecular biology and beyond. His work exemplifies the impact of interdisciplinary collaboration and the enduring pursuit of scientific discovery.

Profile summary based on public USPTO records.
Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]
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