Inventors with similar research interests:
Location History:
- Los Altos Hills, CA (US) (1976 - 1977)
- Los Altos Hill, CA (US) (1977)
- Palo Alto, CA (US) (1986)
- Stanford, CT (US) (1987)
- Stamford, CA (US) (1993)
- Stanford, CA (US) (1981 - 2003)
- Menlo Park, CA (US) (2004 - 2011)
Company Filing History:
43 out of 5,303 
27 out of 24,189 
4 out of 560 Years Active: 1976-2011
Areas of Expertise:
Title: Calvin F. Quate: Pioneering Innovations in Macromolecular Detection
Introduction
Calvin F. Quate is a renowned inventor and researcher based in Stanford, California. With a remarkable portfolio of 75 patents, his contributions have significantly advanced the field of atomic force microscopy and macromolecular detection methods. Quate's innovative approaches have paved the way for novel scientific discoveries and practical applications in molecular biology.
Latest Patents
Among Quate's latest patents are groundbreaking methods for detecting macromolecular complexes on ultraflat surfaces using harmonic cantilevers. His patents detail a method and apparatus that utilizes these cantilevers to measure variations in attractive and repulsive forces due to macromolecular binding, exemplified by the hybridization of single-stranded DNA molecules. The unique properties of complexed macromolecules, such as decreased flexibility and increased negative charge from amino acids or DNA monomers, are pivotal in this detection process. The patents emphasize the use of ultraflat surfaces, including gold-coated mica substrates, to enhance the precision of macromolecule deposition and detection.
Career Highlights
Calvin F. Quate has had an illustrious career, contributing his expertise to prestigious institutions including Leland Stanford Junior University and Xerox Corporation. His work has not only enriched academic circles but has also strengthened industry practices in molecular analysis and detection.
Collaborations
Throughout his career, Quate has collaborated with notable colleagues, including Butrus Thomas Khuri-Yakub and Stephen C. Minne. These collaborations have further propelled his innovative efforts in advancing atomic force microscopy and its applications in various scientific fields.
Conclusion
Calvin F. Quate's contributions to the realm of macromolecular detection represent a significant leap forward in scientific methodology. Through his 75 patents, he has established a legacy of innovation that continues to inspire future generations of inventors and researchers in the field of molecular biology and beyond. His work exemplifies the impact of interdisciplinary collaboration and the enduring pursuit of scientific discovery.
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