Cypress, TX, United States of America

Brian P Stupi




Average Co-Inventor Count = 5.0

ph-index = 9

Forward Citations = 226(Granted Patents)


Location History:

  • Houston, TX (US) (2011 - 2015)
  • Cypress, TX (US) (2012 - 2021)

Company Filing History:


Years Active: 2011-2021

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15 patents (USPTO):Explore Patents

Title: **The Innovative Journey of Brian P. Stupi**

Introduction

Brian P. Stupi is a prominent inventor based in Cypress, TX, USA, known for his contributions to the field of nucleic acid sequencing. With an impressive portfolio of 15 patents, Stupi has established himself as a key figure in the development of innovative methods for DNA and RNA analysis. His work stands at the intersection of biochemistry and technology, significantly advancing the capabilities of genetic research.

Latest Patents

One of Stupi's latest patents includes the invention of **3'-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing**. This invention relates to 3'-OH unblocked nucleotides and nucleosides, both labeled and unlabeled with 5-methoxy-substituted nitrobenzyl-based photocleavable terminating groups. These compounds are designed for use in DNA and RNA sequencing and analysis, serving as reversible terminators. They exhibit fast nucleotide incorporation kinetics, precise single-base termination, high selectivity for nucleotides, and rapid cleavage of terminating groups, resulting in naturally occurring nucleotides. This groundbreaking work enhances the efficiency and accuracy of nucleic acid sequencing methods, paving the way for advancements in genetic research.

Career Highlights

Throughout his career, Brian P. Stupi has worked with leading companies in the biotechnological sector, including LaserGen, Inc. and Agilent Technologies, Inc. His experiences in these organizations have enriched his expertise and contributed to his success as an inventor. Stupi's career reflects a commitment to innovation and excellence in the field of molecular biology.

Collaborations

In his professional journey, Stupi has collaborated with other esteemed scientists, including Weidong Wu and Michael L. Metzker. These collaborations have fostered a spirit of teamwork and mutual innovation, resulting in significant advancements in biotechnology and genetic analysis.

Conclusion

Brian P. Stupi's impact on the field of nucleic acid sequencing is remarkable, characterized by his inventive spirit and collaborative efforts. With a growing portfolio of patents and a dedication to advancing genetic research, Stupi continues to be a vital contributor to the scientific community. His work not only enhances our understanding of molecular biology but also drives the future of genetic technologies.

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