The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2012

Filed:

Jan. 07, 2011
Applicants:

Weidong Wu, Houston, TX (US);

Vladislav A. Litosh, Cypress, TX (US);

Brian P. Stupi, Houston, TX (US);

Michael L. Metzker, Houston, TX (US);

Inventors:

Weidong Wu, Houston, TX (US);

Vladislav A. Litosh, Cypress, TX (US);

Brian P. Stupi, Houston, TX (US);

Michael L. Metzker, Houston, TX (US);

Assignee:

Lasergen, Inc, Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/70 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided are novel nucleotides, nucleoside, and their derivatives described herein, that can be used in DNA sequencing technology and other types of DNA analysis. In one embodiment, the nucleotide or nucleoside with an unprotected 3'-OH group is derivatized at the nucleobase to include a fluorescent dye attached via a linker to a non-cleavable terminating group. The non-cleavable-fluorescent group is designed to terminate DNA synthesis so that DNA oligomers can be sequenced efficiently in a parallel format. These reagents and methods will lead to more accurate identification of polymorphisms and other valuable genetic information.


Find Patent Forward Citations

Wu, Weidong. (2012). 3'-oh unblocked nucleotides and nucleosides base modified with non-cleavable, terminating groups and methods for their use in dna sequencing (U.S. Patent No. 8198029). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8198029

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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