Chapel Hill, NC, United States of America

Bolyn Hubby

USPTO Granted Patents = 7 


 

Average Co-Inventor Count = 3.7

ph-index = 4

Forward Citations = 56(Granted Patents)


Location History:

  • Cary, NC (US) (2012 - 2018)
  • Chapel Hill, NC (US) (2014 - 2020)

Company Filing History:


Years Active: 2012-2020

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7 patents (USPTO):Explore Patents

Title: Bolyn Hubby: Innovator in Alphavirus Research

Introduction

Bolyn Hubby is a prominent inventor based in Chapel Hill, NC (US), known for his significant contributions to the field of virology and immunology. With a total of seven patents to his name, Hubby's work focuses on the development of innovative methods and compositions that enhance immune responses.

Latest Patents

Among his latest patents is the invention titled "TC-83-derived alphavirus vectors, particles and methods." This patent provides a detailed disclosure of TC-83 VEE-derived replicons, alphaviral replicon particles, and immunogenic compositions that utilize these particles to direct the expression of at least one antigen when introduced into a suitable host cell. The TC-83 VEE-derived ARPs described in this patent are noted for their improved characteristics, particularly their reduced vector-specific immune response compared to prior art ARPs. Another notable patent is "Alphavirus replicon particles matched to protein antigens as immunological adjuvants." This invention highlights how the immune response to a specific antigen can be significantly enhanced through the simultaneous administration of an alphavirus replicon particle that expresses the same antigen. This innovative approach allows for the use of smaller quantities of protein antigens, potentially eliminating the need for booster doses in immunization strategies.

Career Highlights

Bolyn Hubby is currently associated with Alphavax, Incorporated, where he continues to advance research in the field of alphavirus vectors and their applications in immunology. His work has been instrumental in developing new strategies for vaccine delivery and immune response enhancement.

Collaborations

Hubby collaborates with notable colleagues, including Jonathan F. Smith and Jon O. Rayner, contributing to a dynamic research environment that fosters innovation and discovery.

Conclusion

Bolyn Hubby's contributions to the field of virology through his patents and research at Alphavax, Incorporated, underscore his role as a leading inventor in the development of advanced immunological strategies. His work continues to pave the way for new approaches in vaccine technology and immune response enhancement.

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