Binbin Kou is a notable inventor based in Bloomington, IN (US). He has made significant contributions to the field of pharmaceutical sciences, particularly in the development of prodrug formulations for insulin and glucagon superfamily peptides. With a total of 5 patents to his name, Kou's work is paving the way for advancements in diabetes treatment.

Latest Patents

Kou's latest patents include innovative formulations that enhance the efficacy of insulin and glucagon. One of his key inventions is the lipidated amide-based insulin prodrugs. These formulations modify the insulin peptide through an amide bond linkage with a dipeptide prodrug element. This modification results in prodrugs that have extended half-lives and are converted to their active forms under physiological conditions via a non-enzymatic reaction driven by chemical instability. Another significant patent involves amide-based glucagon and superfamily peptide prodrugs. Similar to his insulin formulations, these prodrugs are linked to a dipeptide through an amide bond, allowing for extended half-lives and conversion to active forms under physiological conditions.

Career Highlights

Binbin Kou is affiliated with Indiana University, where he conducts research and develops innovative pharmaceutical solutions. His work has garnered attention in the scientific community, contributing to advancements in drug delivery systems and therapeutic efficacy.

Collaborations

Kou collaborates with esteemed colleagues, including Richard Dennis DiMarchi and Shujiang Cheng, who contribute to his research endeavors and enhance the impact of his innovations.

Conclusion

Binbin Kou's contributions to the field of pharmaceutical sciences, particularly in the development of insulin and glucagon prodrugs, highlight his innovative spirit and dedication to improving diabetes treatment. His work continues to inspire advancements in drug formulation and delivery.

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