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For the Inventor, By the Inventor

Amersfoort, Netherlands

Arie Pieter Otte

USPTO Granted Patents = 26 

 

Average Co-Inventor Count = 2.8

ph-index = 5

Forward Citations = 86(Granted Patents)


Company Filing History:

goldMedal21 out of 25 
 
Chromagenics B.v.
 patents
silverMedal5 out of 5 
 
Cellagenics B.v.
 patents

Years Active: 2007-2020

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26 patents (USPTO):Explore Patents
1. 10563223 - Intergenic elements for enhancing gene expression (2020-02-18),
2. 10106799 - Stringent selectable markers (2018-10-23),
3. 9790517 - Intergenic elements for enhancing gene expression (2017-10-17),
4. 9650630 - Nucleic acid fragments from a ribosomal protein promoter for enhancing gene expression (2017-05-16),
5. 9284563 - Stringent selectable markers (2016-03-15),
6. 9228004 - Selection of host cells expressing protein at high levels (2016-01-05),
7. 8999667 - Selection of host cells expressing protein at high levels (2015-04-07),
8. 8771984 - Selection of host cells expressing protein at high levels (2014-07-08),
9. 8263393 - Means and methods for producing a protein through chromatin openers that are capable of rendering chromatin more accessible to transcription factors (2012-09-11),
10. 8173422 - Method for improving protein production (2012-05-08),
11. 8039230 - Selection of host cells expressing protein at high levels (2011-10-18),
12. 7968700 - Expression augmenting DNA fragments, use thereof, and methods for finding thereof (2011-06-28),
13. 7960143 - Method for simultaneous production of multiple proteins; vectors and cells for use therein (2011-06-14),
14. 7901908 - Method for simultaneous production of multiple proteins; vectors and cells for use therein (2011-03-08),
15. 7825232 - Sequence for improving expression of nucleic acid (2010-11-02),

Title: The Innovative Contributions of Arie Pieter Otte

Introduction

Arie Pieter Otte is a prominent inventor based in Amersfoort, Netherlands, known for his significant contributions to biotechnology. With an impressive portfolio of 26 patents, Otte has made remarkable strides in the field of gene expression and eukaryotic host cell development.

Latest Patents

Otte's latest innovations include groundbreaking patents that focus on intergenic elements and stringent selectable markers. One notable invention pertains to nucleic acid fragments and constructs that enhance gene expression by utilizing genomic sequences upstream of Rb1 and p15C. This invention enables the production of gene products of interest in mammalian host cells with the use of stringent selectable markers. Another significant patent involves nucleic acid constructs that comprise selectable marker genes in multicistronic transcription units, aimed at improving the generation and selection of eukaryotic host cells. These advancements highlight Otte's commitment to enhancing biotechnological applications.

Career Highlights

Throughout his career, Arie Pieter Otte has worked with esteemed companies such as Chromagenics B.V. and Cellagenics B.V. His work has not only contributed to the companies' advancements but has also significantly impacted the broader field of biotechnological research.

Collaborations

Otte has collaborated with notable professionals, including Arthur Leo Kruckeberg and Henricus Johannes Maria Van Blokland. These collaborations reflect his dedication to working alongside other experts in the field to innovate and expand the horizons of biotechnology.

Conclusion

Arie Pieter Otte's contributions to innovation in biotechnology through his patents and collaborations underscore his role as a vital figure in the industry. His work continues to influence the development of advanced gene expression techniques and the production of gene products in eukaryotic systems, paving the way for future research and advancements.

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