Antimo Gioiello

Title: Antimo Gioiello: Innovator in Pharmaceutical Modulators

Introduction

Antimo Gioiello is a prominent inventor based in Perugia, Italy. He has made significant contributions to the field of pharmaceuticals, particularly in the development of modulators for various receptors. With a total of 10 patents to his name, Gioiello's work has the potential to impact the treatment of numerous diseases.

Latest Patents

Gioiello's latest patents include innovative compounds related to Farnesoid X receptor (FXR) modulators. The present application provides a compound of formula I or a pharmaceutically acceptable salt, solvate, or amino acid conjugate thereof, wherein R-R, m, n, p, and are as described herein. This invention relates generally to FXR modulators and to methods of making and using said compounds. Another significant patent involves TGR5 modulators and methods of use thereof. This application relates to compounds of formula A or a salt, solvate, ester, tautomer, amino acid conjugate, or metabolite thereof. The compounds of formula A are TGR5 modulators useful for the treatment of various diseases, including metabolic disease, inflammatory disease, autoimmune disease, cardiac disease, kidney disease, cancer, and gastrointestinal disease.

Career Highlights

Antimo Gioiello has established himself as a key figure in the pharmaceutical industry. He is currently associated with Intercept Pharmaceuticals, Inc., where he continues to innovate and develop new therapeutic solutions. His extensive research and development efforts have led to breakthroughs in the understanding and treatment of complex diseases.

Collaborations

Throughout his career, Gioiello has collaborated with notable colleagues, including Roberto Pellicciari and Antonio Macchiarulo. These partnerships have fostered a collaborative environment that enhances the potential for groundbreaking discoveries in the pharmaceutical field.

Conclusion

Antimo Gioiello's contributions to pharmaceutical science, particularly in the area of receptor modulators, highlight his role as an influential inventor. His work not only advances scientific knowledge but also holds promise for improving patient outcomes in various medical conditions.