The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 20, 2021

Filed:

Jun. 22, 2018
Applicant:

Intercept Pharmaceuticals, Inc., New York, NY (US);

Inventors:

Roberto Pellicciari, Perugia, IT;

Antimo Gioiello, Perugia, IT;

Gabriel Galvin, San Diego, CA (US);

Ronald D. Lewis, II, San Diego, CA (US);

Mathew Yanik, San Diego, CA (US);

Myoung Goo Kim, Summerfield, NC (US);

Frederik Ronald Leusink, Zuidhorn, NL;

Bartjan Koning, Aduard, NL;

Thomas Hensel, Groningen, NL;

Assignee:

Intercept Pharmaceuticals, Inc., New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07J 9/00 (2006.01); C07J 31/00 (2006.01);
U.S. Cl.
CPC ...
C07J 9/005 (2013.01); C07J 31/006 (2013.01);
Abstract

The present disclosure relates to methods and novel intermediates useful in the preparation of a compound of formula I or pharmaceutically acceptable salt, hydrate, solvate or amino acid, sulfate or glucuronide conjugate, or prodrug thereof, comprising the step of reacting a compound of formula I-4 with a halogenating reagent to provide a compound of formula I-5a


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