The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2020
Filed:
Jun. 16, 2016
Applicant:
Intercept Pharmaceuticals, Inc., New York, NY (US);
Inventors:
Roberto Pellicciari, Perugia, IT;
Antimo Gioiello, Perugia, IT;
Antonio Macchiarulo, Perugia, IT;
Francoise Perron-Sierra, Paris, FR;
Klaus Seedorf, Hamburg, DE;
Assignee:
Intercept Pharmaceuticals, Inc., New York, NY (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07J 9/00 (2006.01); C07J 43/00 (2006.01); A61P 1/16 (2006.01); C07J 41/00 (2006.01); A61P 3/08 (2006.01);
U.S. Cl.
CPC ...
C07J 9/005 (2013.01); A61P 1/16 (2018.01); A61P 3/08 (2018.01); C07J 41/00 (2013.01); C07J 41/0061 (2013.01); C07J 43/003 (2013.01);
Abstract
The application relates to compounds of formula A: or a salt, solvate, ester, tautomer, amino acid conjugate, or metabolite thereof. The compounds of formula A are TGR5 modulators useful for the treatment of various diseases, including metabolic disease, inflammatory disease, autoimmune disease, cardiac disease, kidney disease, cancer, and gastrointestinal disease.