Poortugaal, Netherlands

Andreas Gerardus Uitterlinden

USPTO Granted Patents = 4 

Average Co-Inventor Count = 3.3

ph-index = 1


Company Filing History:


Years Active: 2004-2010

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4 patents (USPTO):Explore Patents

Title: Inventor Profile: Andreas Gerardus Uitterlinden

Introduction

Andreas Gerardus Uitterlinden is an accomplished inventor based in Poortugaal, Netherlands. With a total of four patents to his name, Uitterlinden has made significant contributions in the field of genetics and bone health, particularly in determining risks associated with altered bone mineral density.

Latest Patents

Uitterlinden's latest innovations include compositions and methods for determining a subject's risk of having or the presence of altered bone mineral density. This particularly focuses on conditions such as osteoporosis or osteopenia. The invention emphasizes the analysis of a sclerostin gene region nucleotide polymorphism (SRP) found in DNA from the sclerostin gene region on human chromosome 17. Notably, certain embodiments indicate that SRPs, which suggest an increased risk of altered bone mineral density, manifest as gender-associated polymorphisms. Additionally, he has developed isolated polynucleotides that comprise representative SRPs.

Another significant patent involves methods for determining susceptibility to bone fractures in mammalian subjects. This entails analyzing nucleic acid molecules to identify which alleles of the estrogen receptor alpha gene are present, specifically focusing on P, p, X, and x alleles. A haplotype that includes the p and x alleles indicates an increased fracture susceptibility. Uitterlinden's patent also provisions for kits designed to assess such susceptibility.

Career Highlights

Throughout his career, Uitterlinden has worked at prestigious institutions such as Erasmus University Rotterdam and Celltech R&D Limited. His research has been critical in the advancement of genetic understanding related to skeletal health and fracture risk.

Collaborations

Uitterlinden has collaborated with prominent researchers in his field, including Johannes Petrus Thomas Maria Van Leeuwen and Huibert Adriaan Pieter Pols. Their combined efforts have propelled innovative research and development in genetic studies and related healthcare solutions.

Conclusion

Andreas Gerardus Uitterlinden exemplifies the impact that innovation can have on public health, particularly through his research and patented inventions related to bone mineral density. His work continues to pave the way for understanding genetic contributions to bone health and fracture risks, signifying his vital role in the scientific community.

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