This inventor holds 4 USPTO granted patents and 7 published patent applications. Top assignees: Erasmus University Rotterdam, Celltech R&d Limited, Century Technology, Inc.. Active years: 2004-2010.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
2 out of 22 
1 out of 68 
1 out of 1 Years Active: 2004-2010
Title: Inventor Profile: Andreas Gerardus Uitterlinden
Introduction
Andreas Gerardus Uitterlinden is an accomplished inventor based in Poortugaal, Netherlands. With a total of four patents to his name, Uitterlinden has made significant contributions in the field of genetics and bone health, particularly in determining risks associated with altered bone mineral density.
Latest Patents
Uitterlinden's latest innovations include compositions and methods for determining a subject's risk of having or the presence of altered bone mineral density. This particularly focuses on conditions such as osteoporosis or osteopenia. The invention emphasizes the analysis of a sclerostin gene region nucleotide polymorphism (SRP) found in DNA from the sclerostin gene region on human chromosome 17. Notably, certain embodiments indicate that SRPs, which suggest an increased risk of altered bone mineral density, manifest as gender-associated polymorphisms. Additionally, he has developed isolated polynucleotides that comprise representative SRPs.
Another significant patent involves methods for determining susceptibility to bone fractures in mammalian subjects. This entails analyzing nucleic acid molecules to identify which alleles of the estrogen receptor alpha gene are present, specifically focusing on P, p, X, and x alleles. A haplotype that includes the p and x alleles indicates an increased fracture susceptibility. Uitterlinden's patent also provisions for kits designed to assess such susceptibility.
Career Highlights
Throughout his career, Uitterlinden has worked at prestigious institutions such as Erasmus University Rotterdam and Celltech R&D Limited. His research has been critical in the advancement of genetic understanding related to skeletal health and fracture risk.
Collaborations
Uitterlinden has collaborated with prominent researchers in his field, including Johannes Petrus Thomas Maria Van Leeuwen and Huibert Adriaan Pieter Pols. Their combined efforts have propelled innovative research and development in genetic studies and related healthcare solutions.
Conclusion
Andreas Gerardus Uitterlinden exemplifies the impact that innovation can have on public health, particularly through his research and patented inventions related to bone mineral density. His work continues to pave the way for understanding genetic contributions to bone health and fracture risks, signifying his vital role in the scientific community.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile