Company Filing History:
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Years Active: 1989-2008
Title: Allen M. Spiegel: Innovator in Tumor Suppressor Gene Research
Allen M. Spiegel, located in Bethesda, MD, is a distinguished inventor with a remarkable portfolio of four patents. His contributions to the field of genetics and biotechnology have significantly advanced our understanding of tumor suppressor genes and their applications in diagnostics and gene therapy.
Latest Patents
Among his latest innovations is the discovery of a novel tumor suppressor gene associated with multiple endocrine neoplasia type 1, designated as MEN1. This gene's product, menin, plays a critical role in cellular functions, and the absence of this protein, along with the mutations in the MEN1 gene, have been identified in patients suffering from multiple endocrine neoplasia type 1. This discovery holds substantial diagnostic utility, along with potential applications in gene therapy. Additionally, Allen's work on antibody reagents that specifically identify a peptide sequence and bind to the GTP-binding protein G_o has expanded the ability to identify and distinguish between different GTP-binding proteins, showcasing his expertise in both gene technology and antibody engineering.
Career Highlights
Throughout his career, Allen has been involved with various esteemed organizations. Notably, he has worked with the United States of America as represented by the Secretary of Health and the United States Department of Health and Human Services. His professional journey reflects a commitment to advancing scientific knowledge and improving public health through innovative research and development.
Collaborations
Collaboration has been a key component of Allen's work. He has partnered with notable colleagues such as Settara Chandrasekharappa and Siradanahalli Guru, contributing to the collective effort in research that addresses critical health issues. Together, they have paved the way for future discoveries that could impact patient care and treatment options in the field of medicine.
Conclusion
In conclusion, Allen M. Spiegel stands out as an influential inventor whose research and patents have significant implications in the realms of genetics and healthcare. With a focus on tumor suppressor genes and antibody development, his work continues to inspire advancements in medical science, benefiting patients and researchers alike.