The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 15, 2008
Filed:
Mar. 04, 1998
Settara Chandrasekharappa, Gaithersburg, MD (US);
Siradanahalli Guru, Bethesda, MD (US);
Pachiappan Manickam, Huntsville, AL (US);
Francis S. Collins, Rockville, MD (US);
Michael R. Emmert-buck, Silver Spring, MD (US);
Larisa V. Debelenko, New York, NY (US);
Irina A. Lubensky, Silver Spring, MD (US);
Lance A. Liotta, Bethesda, MD (US);
Sunita K. Agarwal, Gaithersburg, MD (US);
Allen M. Spiegel, Bethesda, MD (US);
A. Lee Burns, Rockville, MD (US);
Stephen J. Marx, Chevy Chase, MD (US);
Zhengping Zhuang, Bethesda, MD (US);
Settara Chandrasekharappa, Gaithersburg, MD (US);
Siradanahalli Guru, Bethesda, MD (US);
Pachiappan Manickam, Huntsville, AL (US);
Francis S. Collins, Rockville, MD (US);
Michael R. Emmert-Buck, Silver Spring, MD (US);
Larisa V. Debelenko, New York, NY (US);
Irina A. Lubensky, Silver Spring, MD (US);
Lance A. Liotta, Bethesda, MD (US);
Sunita K. Agarwal, Gaithersburg, MD (US);
Allen M. Spiegel, Bethesda, MD (US);
A. Lee Burns, Rockville, MD (US);
Stephen J. Marx, Chevy Chase, MD (US);
Zhengping Zhuang, Bethesda, MD (US);
Abstract
The invention relates to the discovery of a novel tumor suppressor gene which is associated with multiple endocrine neoplasia type 1. The gene has been designated MEN1 and the gene product is menin. The absence of this protein and associated mutations in the corresponding gene have been identified in individuals suffering from multiple endocrine neoplasia type 1. The identification of this marker for multiple endocrine neoplasia type 1 has diagnostic uses as well as for gene therapy.