Company Filing History:
Years Active: 2021-2025
Title: Agustina Rodriguez-Granillo: Pioneering Innovations in Enzyme Technology
Introduction
Agustina Rodriguez-Granillo, based in Rahway, NJ, has established herself as a prominent inventor with a remarkable portfolio of 13 patents. Her innovations primarily focus on enzyme technology, contributing significantly to the fields of biotechnology and pharmaceuticals.
Latest Patents
Among her most recent inventions are two noteworthy patents that revolve around engineered enzyme systems. The first patent involves ketoreductase polypeptides and polynucleotides, showcasing engineered ketoreductase and phosphite dehydrogenase enzymes with enhanced properties compared to naturally occurring variants. These engineered enzymes are integral to synthesizing chiral catalysts used in the development of antiviral compounds, particularly nucleoside inhibitors. Furthermore, her methods allow for the deracemization of chiral alcohols in a streamlined, one-pot, multi-enzyme system.
The second patent focuses on engineered purine nucleoside phosphorylase (PNP) enzymes, offering novel polypeptides with PNP activity. This invention includes various methods for producing these enzymes, alongside compositions that utilize them. The engineered PNP enzymes hold significant promise for the production of important pharmaceutical compounds.
Career Highlights
Agustina is currently affiliated with Codexis, Inc., where she leverages her expertise in enzyme engineering to drive forward-thinking innovations. Her career is characterized by a commitment to advancing biocatalysis and its applications in developing new therapeutic agents.
Collaborations
Throughout her career, Agustina has collaborated with talented professionals such as Jovana Nazor and Oscar Alvizo. These collaborations enhance the impact of her inventions, bringing together diverse skills and insights within the scientific community.
Conclusion
Agustina Rodriguez-Granillo continues to inspire through her groundbreaking work in enzyme technology. Her patents and innovations stand as a testament to her dedication to science and the potential for biotechnological applications in pharmaceuticals. As she advances her research and development efforts, the future holds great promise for her contributions to the field.