The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 15, 2021

Filed:

Jul. 02, 2019
Applicant:

Codexis, Inc., Redwood City, CA (US);

Inventors:

Scott J. Novick, Palo Alto, CA (US);

Xiang Yi, Foster City, CA (US);

Nikki Dellas, Mountain View, CA (US);

Oscar Alvizo, Fremont, CA (US);

Jovana Nazor, Milpitas, CA (US);

Da Duan, Newark, CA (US);

Vesna Mitchell, Santa Clara, CA (US);

Jonathan Vroom, South San Francisco, CA (US);

Santhosh Sivaramakrishnan, Redwood City, CA (US);

Nandhitha Subramanian, San Francisco, CA (US);

Jeffrey C. Moore, Westfield, NJ (US);

Mark Huffman, Rahway, NJ (US);

Agustina Rodriguez-Granillo, Rahway, NJ (US);

Deeptak Verma, Rahway, NJ (US);

Grant Murphy, Rahway, NJ (US);

Nicholas M. Marshall, Rahway, NJ (US);

Jay Russell, Rahway, NJ (US);

Keith A. Canada, Freehold, NJ (US);

Assignee:

Codexis, Inc., Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/52 (2006.01); C12N 9/90 (2006.01); C12N 15/74 (2006.01); C12N 15/81 (2006.01);
U.S. Cl.
CPC ...
C12N 9/90 (2013.01); C12N 15/52 (2013.01); C12N 15/74 (2013.01); C12N 15/815 (2013.01); C12Y 504/02007 (2013.01);
Abstract

The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.


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