The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 2021
Filed:
Jul. 02, 2019
Codexis, Inc., Redwood City, CA (US);
Scott J. Novick, Palo Alto, CA (US);
Nikki Dellas, Mountain View, CA (US);
Vesna Mitchell, Santa Clara, CA (US);
Da Duan, Newark, CA (US);
Jovana Nazor, Milpitas, CA (US);
Oscar Alvizo, Fremont, CA (US);
Auric Anthony Sowell-Kantz, Fairfax, CA (US);
Jeffrey C. Moore, Westfield, NJ (US);
Mark Huffman, Rahway, NJ (US);
Agustina Rodriguez-Granillo, Rahway, NJ (US);
Deeptak Verma, Rahway, NJ (US);
Nicholas M. Marshall, Rahway, NJ (US);
Jay Russell, Rahway, NJ (US);
Keith A. Canada, Freehold, NJ (US);
Codexis, Inc., Redwood City, CA (US);
Abstract
The present invention provides engineered purine nucleoside phosphorylase (PNP) enzymes, polypeptides having PNP activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PNP enzymes are also provided. The present invention further provides compositions comprising the PNP enzymes and methods of using the engineered PNP enzymes. The present invention finds particular use in the production of pharmaceutical compounds.