Company Filing History:
Years Active: 2011-2014
Title: **Innovative Contributions of Adriana Caterina Maggi in the Field of Pharmacology**
Introduction
Adriana Caterina Maggi is a notable inventor based in Milan, Italy, recognized for her significant contributions to pharmacology through her innovative inventions. With a total of three patents, her work primarily focuses on the development of transgenic models and novel therapeutic compounds.
Latest Patents
One of Adriana's most remarkable patents involves a transgenic mouse for screening and for studies of the pharmacodynamics and pharmacokinetics of ligands acting on the oestrogen receptor and its intracellular receptors. This invention introduces a method for the production of a non-human transgenic mammal, specifically a mouse, that allows researchers to monitor in vivo the state of activation of various intracellular receptors. The method utilizes a reporter gene inducible by either natural or synthetic molecules that modulate receptor activity.
Another noteworthy patent focuses on 17-alpha-substituted derivatives of estradiol with wound-healing activity. This invention encompasses a series of compounds, specifically 17-alpha-(5-hydroxy-C-hydrocarbyl)-1,3,5(10)-estratrien-3,17-beta-diol derivatives, known for their cicatrising properties. These derivatives are designed for topical application to wounds, minimizing significant systemic effects compared to traditional treatments. The invention also includes specific estradiol derivatives and outlines the method for their preparation through a series of chemical reactions.
Career Highlights
Throughout her career, Adriana Caterina Maggi has collaborated with prominent companies in the biopharmaceutical sector, including Transgenic Operative Products S.R.L. and Euticals Spa. Her role in these companies has allowed her to apply her innovative methodologies in practical settings and contribute to advancements in medical treatments.
Collaborations
Adriana has worked closely with esteemed colleagues, such as Paolo Ciana and Gillian Ashcroft. These collaborations have facilitated the sharing of ideas and expertise, further enhancing the impact of her inventions in the field of pharmacology.
Conclusion
Adriana Caterina Maggi's inventive spirit and dedication to research demonstrate her vital role as a leading innovator in pharmacology. Her patents reflect a commitment to improving healthcare outcomes, showcasing the importance of innovation in developing effective treatments for various medical conditions. As she continues her work in this field, her contributions are anticipated to pave the way for further advancements and discoveries.