The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2014
Filed:
Mar. 31, 2011
Applicants:
Adriana Caterina Maggi, Milan, IT;
Paolo Ciana, Gravellona Toce, IT;
Inventors:
Adriana Caterina Maggi, Milan, IT;
Paolo Ciana, Gravellona Toce, IT;
Assignee:
T.O.P. (Transgenic Operative Products) S.R.L., Cascina Codazza, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/00 (2006.01); A01K 67/027 (2006.01); A01N 63/00 (2006.01); C12N 15/00 (2006.01); C12N 15/63 (2006.01); C12N 15/79 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0275 (2013.01); A01K 2227/105 (2013.01); A01K 2267/03 (2013.01); C12N 15/79 (2013.01); C12N 15/8509 (2013.01); G01N 2333/72 (2013.01);
Abstract
The object of the invention is a method for the production of a non-human transgenic mammal by means of which it is possible to monitor in vivo and in all the tissues the state of activation of any intracellular receptor, utilizing a reporter gene inducible by natural or synthetic molecules which modulate the activity of such receptor. The mammal is question is preferably a mouse.
Maggi, Adriana. (2014). Transgenic mouse for screening and for studies of the pharmacodynamics and pharmacokinetics of ligands acting on the oestrogen receptor and its intracellular receptors, and method for the preparation thereof (U.S. Patent No. 8809618). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8809618
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile