The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2014

Filed:

Jun. 03, 2008
Applicants:

Catherine Tachdjian, San Diego, CA (US);

Donald S. Karanewsky, Escondido, CA (US);

Xiao-qing Tang, San Diego, CA (US);

Xiaodong LI, San Diego, CA (US);

Feng Zhang, San Diego, CA (US);

Guy Servant, San Diego, CA (US);

Qing Chen, San Diego, CA (US);

Vincent Darmohusodo, Encinitas, CA (US);

Richard Fine, Ridgewood, NJ (US);

Joseph R. Fotsing, San Diego, CA (US);

Jeffrey Robert Hammaker, San Diego, CA (US);

Xinshan Kang, Pine Brook, NJ (US);

Rachel D. A. Kimmich, San Diego, CA (US);

Boris Klebansky, Demarest, NJ (US);

Haitian Liu, San Diego, CA (US);

Goran Petrovic, San Diego, CA (US);

Marketa Rinnova, Urbana, IL (US);

Sara Adamski-werner, San Diego, CA (US);

Jeffrey Yamamoto, San Diego, CA (US);

Hong Zhang, San Diego, CA (US);

Albert Zlotnik, San Diego, CA (US);

Karen Zoller, La Jolla, CA (US);

Inventors:

Catherine Tachdjian, San Diego, CA (US);

Donald S. Karanewsky, Escondido, CA (US);

Xiao-Qing Tang, San Diego, CA (US);

Xiaodong Li, San Diego, CA (US);

Feng Zhang, San Diego, CA (US);

Guy Servant, San Diego, CA (US);

Qing Chen, San Diego, CA (US);

Vincent Darmohusodo, Encinitas, CA (US);

Richard Fine, Ridgewood, NJ (US);

Joseph R. Fotsing, San Diego, CA (US);

Jeffrey Robert Hammaker, San Diego, CA (US);

Xinshan Kang, Pine Brook, NJ (US);

Rachel D. A. Kimmich, San Diego, CA (US);

Boris Klebansky, Demarest, NJ (US);

Haitian Liu, San Diego, CA (US);

Goran Petrovic, San Diego, CA (US);

Marketa Rinnova, Urbana, IL (US);

Sara Adamski-Werner, San Diego, CA (US);

Jeffrey Yamamoto, San Diego, CA (US);

Hong Zhang, San Diego, CA (US);

Albert Zlotnik, San Diego, CA (US);

Mark Zoller, La Jolla, CA (US);

Assignee:

Senomyx Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/95 (2006.01); C07D 285/16 (2006.01); A61K 31/517 (2006.01); A61K 31/54 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention includes methods for identifying modifiers of chemosensory receptors and their ligands, e.g., by determining whether a test entity is suitable to interact with one or more interacting sites within the Venus flytrap domains of the chemosensory receptors, and modifiers capable of modulating chemosensory receptors and their ligands. The present invention also includes modifiers of chemosensory receptors and their ligands having Formula (I), its subgenus, and specific compounds. Furthermore, the present invention includes ingestible compositions comprising the modifiers of chemosensory receptors and their ligands and methods of using the modifiers of chemosensory receptors and their ligands to enhance the sweet taste of an ingestible composition or treat a condition associated with a chemosensory receptor. In addition, the present invention include processes for preparing the modifiers of chemosensory receptors and their ligands.


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