The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2000
Filed:
Oct. 16, 1997
Applicant:
Inventors:
Daniel Bartfeld, Vancouver, CA;
Michael J Butler, Cambridge, GB;
Dany Hadary, Vancouver, CA;
David L Jenish, Mississauga, CA;
Timothy J Krieger, Richmond, CA;
Lawrence T Malek, Brampton, CA;
Gisela Soostmeyer, Kleinburg, CA;
Eva Walczyk, Mississuaga, CA;
Phyllis Krygsman, Brampton, CA;
Sheila Garven, Oakville, CA;
Assignee:
Cangene Corporation, Mississauga, CA;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ; A61K / ;
U.S. Cl.
CPC ...
435 691 ; 4352521 ; 435212 ; 530331 ;
Abstract
An aminopeptidase inhibitor is used when expressing heterologous protein in a bacterial host, such as Streptomyces. Use of such an inhibitor inhibits degradation of the heterologous protein by aminopeptidases. Inhibitors are designed based upon the mechanism and substrate specificity of the target protease and expressed protein.