Company Filing History:
8 out of 13 
4 out of 1,248 
1 out of 1 Years Active: 1992-2002
**Title: Inventor Spotlight: Lawrence T. Malek**
Introduction
Lawrence T. Malek is a notable inventor based in Brampton, Canada, who has made significant contributions to the field of biotechnology through his innovative inventions. With a portfolio of 14 patents, he has been instrumental in developing cutting-edge solutions that address complex challenges in genetic disease diagnosis and protein expression.
Latest Patents
Among his latest patents, Malek has developed a "Subtractive amplification kit useful in the diagnosis of genetic disease mutation or variation." This innovative kit is designed to preferentially amplify target RNA in a sample, enhancing the detection of specific genetic variations. The kit utilizes driver sequences that are complementary to non-target RNA, enabling efficient hybridization and amplification of the target RNA.
Another significant patent is focused on the "Method for expression of proteins in bacterial host cells." This method employs an aminopeptidase inhibitor to protect heterologous proteins during their expression in bacterial systems like Streptomyces. By inhibiting degradation by aminopeptidases, this technique enhances protein yields and stability.
Career Highlights
Lawrence T. Malek has worked with prominent companies such as Cangene Corporation and Akzo Nobel N.V., where he has honed his expertise in biotechnology and innovation. His impressive track record showcases his commitment to advancing scientific knowledge and practical applications in the industry.
Collaborations
Throughout his career, Malek has collaborated with talented individuals in the field, including coworkers Cheryl Davey and Robert T. Garvin. These collaborations have further enriched his work and allowed for the exchange of ideas that drive innovation forward.
Conclusion
Lawrence T. Malek exemplifies the spirit of innovation in the biotechnology sector. With his impressive array of patents and dedication to research, he continues to contribute valuable advancements to the field, paving the way for improved diagnostic and therapeutic approaches in genetic medicine.