This inventor holds 3 USPTO granted patents and 1 published patent application. Top assignee: Cangene Corporation. Active years: 1997-2000.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Brampton, CA (1997 - 1999)
- Richmond, CA (2000)
Company Filing History:
Years Active: 1997-2000
Title: The Innovations of Timothy J Krieger
Introduction
Timothy J Krieger is a notable inventor based in Richmond, CA. He has made significant contributions to the field of biotechnology, particularly in the expression of proteins in bacterial host cells. With a total of 3 patents to his name, Krieger's work has advanced the understanding of protein expression and degradation.
Latest Patents
Krieger's latest patents include a method for the expression of proteins in bacterial host cells. This method utilizes an aminopeptidase inhibitor to prevent the degradation of heterologous proteins by aminopeptidases. The inhibitors are designed based on the mechanism and substrate specificity of the target protease and the expressed protein. Another significant patent focuses on Streptomyces proteases and methods for improved secretion of proteins. This patent identifies a family of proteases that degrade heterologous proteins secreted from Streptomyces host cells. The proteases include tripeptidyl aminopeptidase-Streptomyces and other proteases that can degrade certain substrates under specific conditions. Krieger's innovative approaches have led to the design of irreversible inhibitors and the selection of hosts that secrete high amounts of proteases.
Career Highlights
Timothy J Krieger is currently associated with Cangene Corporation, where he continues to contribute to advancements in biotechnology. His work has been instrumental in developing methods that enhance protein expression and stability in bacterial systems.
Collaborations
Krieger has collaborated with notable colleagues, including Dany Hadary and Lawrence T Malek. These collaborations have fostered a productive environment for innovation and research in the field.
Conclusion
Timothy J Krieger's contributions to biotechnology through his patents and collaborations highlight his role as a significant inventor in the field. His innovative methods for protein expression and degradation prevention continue to influence research and development in biotechnology.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile