Company Filing History:
Years Active: 2019-2024
Title: Zhiyi Sun: Innovator in Nucleotide Analysis
Introduction
Zhiyi Sun is a prominent inventor based in Gloucester, MA (US), known for his significant contributions to the field of nucleotide analysis. With a total of 7 patents to his name, he has made remarkable advancements in understanding modified nucleotides, particularly in the context of DNA.
Latest Patents
Zhiyi Sun's latest patents focus on compositions and methods for analyzing modified nucleotides. One of his notable inventions provides methods for identifying the presence, location, and phasing of methylated and/or hydroxymethylated cytosines in nucleic acids, including long stretches of DNA. This method involves reacting a portion of a nucleic acid sample with a dioxygenase and optionally a glucosyltransferase, followed by a reaction with a cytidine deaminase to detect and map cytosines in DNA. Another patent outlines a method for identifying modified cytosines in nucleic acids, which includes comparing sequences from treated and untreated samples to determine modifications.
Career Highlights
Zhiyi Sun is currently employed at New England Biolabs, Inc., where he continues to innovate in the field of molecular biology. His work has been instrumental in advancing techniques for analyzing nucleic acids, which are crucial for various applications in genetics and biotechnology.
Collaborations
Zhiyi has collaborated with notable colleagues such as Shengxi Guan and Romualdas Vaisvila, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Zhiyi Sun's contributions to nucleotide analysis exemplify the impact of innovative research in biotechnology. His patents not only enhance our understanding of DNA modifications but also pave the way for future advancements in genetic research.
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