Company Filing History:
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1 out of 1 Years Active: 2022-2024
Title: Zhenhua Tian: Innovator in Enzymatic Preparation Methods
Introduction
Zhenhua Tian is a prominent inventor based in Shanghai, China. He has made significant contributions to the field of biotechnology, particularly in the development of methods for the enzymatic preparation of chiral compounds. With a total of 8 patents to his name, Tian's work has garnered attention for its efficiency and innovation.
Latest Patents
One of Tian's latest patents is a method for the enzymatic preparation of R-3-aminobutyric acid. This method boasts high efficiency and high stereoselectivity, utilizing aspartase with stereoisomerization catalytic activity to convert butenoic acid into R-3-aminobutyric acid. The process achieves a conversion rate of ≥98% within just 24 hours, with an enantiomeric excess (ee) value of ≥99.9%. This innovative approach significantly improves conversion efficiency, shortens reaction time, and reduces production costs. The method is characterized by a high yield, low costs, a short production cycle, and ease of scalability, making it suitable for mass production.
Another notable patent involves the use of stereoselective transaminase in the asymmetric synthesis of chiral amines. This patent describes the application of a polypeptide in producing chiral amines or downstream products derived from chiral amines. The method includes culturing a strain that expresses the polypeptide to obtain the desired chiral amine. The stereoselective transaminase has a broad substrate spectrum, indicating its potential for widespread application in chiral amine preparation.
Career Highlights
Throughout his career, Zhenhua Tian has worked with several notable companies, including Abiochem Biotechnology Co., Ltd. and Shanghai Qizhou Ziyue Biotechnology Co., Ltd. His expertise in enzymatic processes has positioned him as a key figure in the biotechnology sector.
Collaborations
Tian has collaborated with several professionals in his field, including Zhanbing Cheng and Shaonan Ding. These collaborations have contributed to the advancement of his research and the successful development of his patented methods.
Conclusion
Zhenhua Tian's innovative work in enzymatic preparation methods has made a significant impact in biotechnology. His patents reflect a commitment to efficiency and sustainability in the production of chiral compounds. As
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