The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
Jan. 05, 2018
Applicant:
Abiochem Biotechnology Co., Ltd., Shanghai, CN;
Inventors:
Assignee:
ABIOCHEM BIOTECHNOLOGY CO., LTD., Shanghai, CN;
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/88 (2006.01); C12N 1/16 (2006.01); C12N 1/20 (2006.01); C12P 13/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/88 (2013.01); C12N 1/16 (2013.01); C12N 1/20 (2013.01); C12P 13/004 (2013.01); C12Y 401/02037 (2013.01);
Abstract
The invention provides a highly active S-cyanohydrin lyase obtained by mutating an amino acid residue at position 103 of a wild-type cassava S-cyanohydrin lyase. The mutation can significantly increase an expression of a mutant enzyme inand does not require a decrease in temperature when induced. Further mutations at position 128 and other sites were performed to obtain mutants with increased catalytic activity.