Zhanbing Cheng

Title: Zhanbing Cheng: Innovator in Enzymatic Synthesis

Introduction

Zhanbing Cheng is a prominent inventor based in Shanghai, China. He has made significant contributions to the field of enzymatic synthesis, holding a total of 8 patents. His innovative methods have advanced the production of chiral amines and other valuable compounds.

Latest Patents

One of Cheng's latest patents is a method for the enzymatic preparation of R-3-aminobutyric acid. This method boasts high efficiency and high stereoselectivity, utilizing aspartase with stereoisomerization catalytic activity to convert butenoic acid into R-3-aminobutyric acid. Remarkably, after just 24 hours of reaction, the conversion rate reaches ≥98%, with an enantiomeric excess (ee) value of ≥99.9%. This method not only improves conversion efficiency but also shortens reaction time and reduces production costs. It features a high yield, low costs, a short production cycle, and is suitable for mass production.

Another notable patent involves the use of stereoselective transaminase in the asymmetric synthesis of chiral amines. This method includes the use of a polypeptide to produce a chiral amine or its downstream products. The process involves culturing a strain that expresses the polypeptide to obtain the desired chiral amine. The stereoselective transaminase has a broad substrate spectrum, indicating its potential for wide application in chiral amine preparation.

Career Highlights

Cheng has worked with several companies, including Abiochem Biotechnology Co., Ltd. and Shanghai Qizhou Ziyue Biotechnology Co., Ltd. His work in these organizations has contributed to the advancement of biotechnological applications in the synthesis of complex molecules.

Collaborations

Cheng has collaborated with notable colleagues such as Zhenhua Tian and Shaonan Ding. Their combined expertise has furthered research and development in the field of enzymatic synthesis.

Conclusion

Zhanbing Cheng is a distinguished inventor whose innovative methods in enzymatic synthesis have made a significant impact in the field. His contributions continue to pave the way for advancements in biotechnology and the production of valuable compounds.