Zhengliang L Wu

Title: The Innovative Contributions of Zhengliang L Wu

Introduction

Zhengliang L Wu is a notable inventor based in Edina, MN (US). He has made significant contributions to the field of biochemistry, particularly in the development of methods and kits for assaying enzyme activities. With a total of 7 patents to his name, Wu's work has advanced the understanding of glycosyltransferase and endoglycosidase activities.

Latest Patents

Wu's latest patents include innovative methods for assaying endoglycosidase activity. This method involves providing a proteoglycan with a glycosaminoglycan chain, treating it with a glycosyltransferase, and incorporating a carbohydrate with a click chemistry moiety. The process continues with the addition of a label that reacts with the carbohydrate, leading to the formation of a labeled proteoglycan. This labeled proteoglycan is then immobilized on a multi-well plate for detection using a specific anti-proteoglycan antibody. Another significant patent is the phosphatase coupled glycosyltransferase assay, which includes a kit for detecting glycosyltransferase activity. This kit combines a phosphatase and a free phosphate detector to measure the activity of the glycosyltransferase enzyme.

Career Highlights

Throughout his career, Wu has worked with prominent companies such as Bio-Techne Corporation and Research & Diagnostics Systems, Inc. His experience in these organizations has allowed him to refine his skills and contribute to groundbreaking research in his field.

Collaborations

Wu has collaborated with notable colleagues, including Robert D Rosenberg and Xinyi Huang. These partnerships have fostered a collaborative environment that enhances innovation and research outcomes.

Conclusion

Zhengliang L Wu's contributions to biochemistry through his patents and collaborations highlight his role as a leading inventor in the field. His innovative methods for assaying enzyme activities continue to impact research and development in biochemistry.