San Diego, CA, United States of America

Zeling Cai

USPTO Granted Patents = 21 


 

Average Co-Inventor Count = 5.4

ph-index = 7

Forward Citations = 127(Granted Patents)


Company Filing History:


Years Active: 2001-2013

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21 patents (USPTO):Explore Patents

Title: The Pioneering Work of Zeling Cai in Innovative Cell Therapies

Introduction

Zeling Cai is an accomplished inventor based in San Diego, California, with an impressive record of 21 patents to his name. His innovations primarily focus on advancements in immunotherapy and cell therapy, addressing critical medical challenges, particularly in oncology.

Latest Patents

Cai's latest patent work includes the preparation of inactivated artificial antigen presenting cells (aAPCs) and their application in cell therapies. His methods involve processing these cells to enhance their functionality in therapeutic compositions, especially for activated cytotoxic T lymphocytes. Notably, he utilizes a crosslinking technique involving a photoreaction with a psoralen derivative and UVA irradiation, demonstrating a novel approach to cell modification. Another significant patent revolves around the identification of antigenic peptides from multiple myeloma cells, a vital step towards developing effective immunotherapies. By targeting specific MHC Class I, HLA-A2 associated peptides, Cai aims to create activated T lymphocytes that can effectively combat multiple myeloma, a disease notorious for its poor prognosis and limited treatment options.

Career Highlights

Zeling Cai's career spans notable roles in leading pharmaceutical companies, including Ortho-McNeil Pharmaceutical Corp. and Janssen Pharmaceutica NV. His contributions have significantly impacted the field of biotechnology, particularly in developing methodologies that enhance the capabilities of immune cells to recognize and fight cancer cells.

Collaborations

Throughout his career, Cai has collaborated with talented colleagues such as Per A. Peterson and Michael R. Jackson. These partnerships have fostered creativity and innovation in the fast-evolving domain of cell therapy and therapeutics, leading to groundbreaking advancements in cancer treatment.

Conclusion

Zeling Cai's groundbreaking innovations and patents illustrate his dedication to improving treatment outcomes in immunotherapy. His ongoing work in developing artificial antigen presenting cells and identifying therapeutic peptides positions him as a key figure in the quest for more effective cancer treatments. As he continues to push the boundaries of biotechnology, his contributions will undoubtedly leave a lasting impact on the field.

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