The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2012
Filed:
Oct. 04, 2007
Zeling Cai, San Diego, CA (US);
Ann Moriarty, Poway, CA (US);
Juli Degraw, San Diego, CA (US);
Didier Leturcq, San Diego, CA (US);
Wei-xing Shi, San Diego, CA (US);
Karen Kabat Stegman, Encinitas, CA (US);
Xilian Yue, San Diego, CA (US);
Zeling Cai, San Diego, CA (US);
Ann Moriarty, Poway, CA (US);
Juli Degraw, San Diego, CA (US);
Didier Leturcq, San Diego, CA (US);
Wei-Xing Shi, San Diego, CA (US);
Karen Kabat Stegman, Encinitas, CA (US);
Xilian Yue, San Diego, CA (US);
Janssen Pharmaceutica N.V., Beerse, BE;
Abstract
Methods of processing inactivated artificial antigen presenting cells (aAPCs) and artificial antigen presenting cells with specificity for selected antigenic peptides are described, including their generation and use in cell therapy compositions comprising activated cytotoxic T lymphocytes. Inactivated aAPCs are advantageously generated through crosslinking, such as via a photoreaction involving a psoralen derivative and UVA irradiation.