San Diego, CA, United States of America

Wei-Xing Shi

USPTO Granted Patents = 14 


 

Average Co-Inventor Count = 5.3

ph-index = 3

Forward Citations = 40(Granted Patents)


Company Filing History:


Years Active: 2010-2013

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14 patents (USPTO):Explore Patents

Title: Innovator Wei-Xing Shi: Advancements in Cell Therapy and Immunotherapy

Introduction

Wei-Xing Shi is a prominent inventor based in San Diego, CA, with a significant contribution to the field of immunotherapy and cell therapies. With a total of 14 patents to his name, Shi has pioneered research that enhances the understanding and treatment of diseases such as multiple myeloma.

Latest Patents

Among Wei-Xing Shi's latest innovations are two critical patents:

1. **Preparation of Inactivated Artificial Antigen Presenting Cells and Their Use in Cell Therapies**: This patent describes methods for processing inactivated artificial antigen presenting cells (aAPCs), which play a crucial role in cell therapy compositions that include activated cytotoxic T lymphocytes. The methodology includes generating inactivated aAPCs through crosslinking, with innovations such as a photoreaction involving psoralen derivatives and UVA irradiation.

2. **Identification of Antigenic Peptides from Multiple Myeloma Cells**: This patent addresses the challenge of treating multiple myeloma (MM), a clonal B cell malignancy. The methods outlined focus on creating activated T lymphocytes that can target and destroy both peptide-loaded T2 target cells and multiple myeloma cell lines, moving towards the development of viable immunotherapies for this aggressive cancer.

Career Highlights

Wei-Xing Shi has a distinguished career, contributing valuable insights and research in pharmaceutical and medical technology. He has worked with notable companies such as Ortho-McNeil Pharmaceutical Corp. and Janssen Pharmaceutica NV, enriching his experience and expertise in the field.

Collaborations

Throughout his career, Shi has collaborated with talented individuals such as Zeling Cai and Juli Degraw. These partnerships have likely facilitated innovative solutions in his research areas and contributed to the success of his patented technologies.

Conclusion

Wei-Xing Shi's dedication to innovation in cell therapy and immunotherapy positions him as a significant contributor to medical advancements. His patents reflect not only his expertise but also his commitment to improving patient outcomes in challenging diseases like multiple myeloma. As research in these areas continues to evolve, Shi’s work remains foundational in the quest for effective therapies.

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