Location History:
- San Diego, CA (US) (1988 - 1993)
- Poway, CA (US) (1996 - 2015)
Company Filing History:
11 out of 1,187 
4 out of 122 
3 out of 2,078 
Years Active: 1988-2015
Title: Ann M Moriarty - Innovator in Cell Therapy for Tumor Treatment
Introduction
Ann M Moriarty, based in Poway, California, is an accomplished inventor with an impressive portfolio of 20 patents. Her work primarily focuses on groundbreaking cell therapy methods designed to enhance immune responses against tumors in cancer patients.
Latest Patents
One of Ann's latest patented innovations involves an advanced cell therapy method aimed at treating tumors. The method addresses the challenge of diminished T cell responses in individuals with compromised immune systems. Ann's innovative approach enables the isolation, stimulation, and expansion of naive cytotoxic T lymphocyte precursors (CTLp) into antigen-specific effectors. These effectors are capable of lysing tumor cells in vivo, marking a significant advancement in cancer treatment. The ex vivo protocol she developed produces functional effectors using artificial antigen presenting cells (AAPCs) transfected with human HLA class I and defined accessory molecules. This system is adaptable, allowing for treatment against a wide array of cancers impacting a significant portion of the population.
Career Highlights
Throughout her career, Ann has made substantial contributions to the fields of immunology and oncology. She has collaborated with prestigious institutions such as The Scripps Research Institute and Scripps Clinic and Research Foundation, where her research has pushed the boundaries of cell therapy applications.
Collaborations
Notable collaborations include working with distinguished colleagues Didier J Leturcq and Richard J Ulevitch. These partnerships have been instrumental in advancing her research and patent developments, fostering innovations that aim to improve treatment outcomes for cancer patients.
Conclusion
Ann M Moriarty's contributions to science and medicine, particularly in the realm of cell therapy, reflect her commitment to fighting cancer through innovative solutions. Her patents and collaborations highlight her role as a leading inventor dedicated to enhancing immune response and improving therapeutic options for patients worldwide.