Company Filing History:
3 out of 15 
1 out of 1 
1 out of 1 Years Active: 2009-2023
Title: Zbynek Prokop: Innovator in Protein Thermostabilization
Introduction
Zbynek Prokop is a notable inventor based in Brno, Czech Republic. He has made significant contributions to the field of protein research, particularly in the area of thermostabilization. With a total of 4 patents, his work has implications in cell biology, regenerative medicine, and cosmetics.
Latest Patents
One of Prokop's latest patents is titled "Thermostable FGF2 polypeptide, use thereof." This invention provides an isolated thermostable polypeptide that possesses FGF2 activity, with at least 85% sequence identity to SEQ ID NO: 2 (FGF2 wt) or a functional fragment thereof. It includes at least one amino acid substitution, R31L, and outlines its use in cell biology research, regenerative medicine, and related medical applications or cosmetics. Additionally, it discloses a culture medium comprising subjected FGF2 suitable for culturing human pluripotent stem cells, including both human embryonic stem cells and induced pluripotent stem cells.
Another significant patent is the "Method of thermostabilization of a protein and/or stabilization towards organic solvents." This method involves the thermostabilization of a protein that contains access routes, where at least one amino acid in the bottleneck of the access route is mutated. The process includes identifying the amino acids of the bottleneck and those that control the exchange of solvent between a buried protein core and the surrounding environment. The modifications aim to improve the packing of amino acids inside the tunnel, preventing undesired solvent molecules from accessing the protein core while allowing necessary compounds to pass through.
Career Highlights
Zbynek Prokop has worked with esteemed institutions such as Masaryk University and Enantis s.r.o. His research and innovations have positioned him as a key figure in the field of protein research.
Collaborations
Throughout his career, Prokop has collaborated with notable colleagues, including Jiri Damborsky and Veronika Stepankova. Their combined expertise has contributed to advancements in the understanding and application of protein thermostabilization.
Conclusion
Zbynek Prokop's innovative work in protein thermostabilization and his contributions to regenerative medicine highlight his importance in the scientific community. His patents reflect a commitment to advancing research in cell biology and related
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.