Norristown, PA, United States of America

Yuri D Ivashchenko


Average Co-Inventor Count = 4.8

ph-index = 2

Forward Citations = 24(Granted Patents)


Location History:

  • Audubon, PA (US) (1996)
  • Norristown, PA (US) (2005 - 2008)
  • Hatersheim, DE (2011)

Company Filing History:


Years Active: 1996-2011

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5 patents (USPTO):Explore Patents

Title: Innovations and Contributions of Inventor Yuri D Ivashchenko

Introduction

Yuri D Ivashchenko is a notable inventor based in Norristown, PA (US). He has made significant contributions to the field of biotechnology, particularly in the development of therapeutic applications related to human proteins and signaling pathways. With a total of 5 patents, his work has had a considerable impact on medical research and treatment options.

Latest Patents

One of Ivashchenko's latest patents is focused on AKT nucleic acids, polypeptides, and their uses. This invention pertains to human Akt3 proteins and polypeptides, as well as isolated nucleic acids encoding human Akt3. The therapeutic applications of this invention are particularly relevant for gene therapy, as the expression of Akt3 has been shown to inhibit cell death associated with hypoxia, apoptosis, or necrosis. Another significant patent involves variants of TRAF2 that act as inhibitors of the TNF-alpha signaling pathway. This invention includes a splice variant of TRAF2 known as 'TRAF2 truncated' and a TRAF2 expression construct with enhanced dominant negative properties, referred to as 'TRAF2 truncated-deleted'. Both variants demonstrate the ability to inhibit the TNF-alpha signaling pathway, with TRAF2TD exhibiting greatly enhanced inhibitory effects.

Career Highlights

Throughout his career, Ivashchenko has worked with prominent companies in the pharmaceutical industry, including Aventis Pharmaceuticals Inc. and Rhone-Poulenc Rorer Pharmaceuticals Inc. His experience in these organizations has contributed to his expertise in the development of innovative therapeutic solutions.

Collaborations

Ivashchenko has collaborated with notable professionals in his field, including Kun Guo and Marco Pagnoni. These collaborations have likely enriched his research and contributed to the success of his inventions.

Conclusion

Yuri D Ivashchenko's contributions to biotechnology and his innovative patents highlight his role as a significant inventor in the field. His work continues to influence therapeutic approaches and medical research.

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