Location History:
- Evanston, IL (US) (2006)
- Gainesville, FL (US) (2006 - 2022)
Company Filing History:
11 out of 2,932 
6 out of 2,123 
Years Active: 2006-2024
Title: Innovations and Contributions of Yunwei Charles Cao
Introduction
Yunwei Charles Cao is a prominent inventor based in Gainesville, FL (US). He has made significant contributions to the field of nanotechnology and catalysis, holding a total of 17 patents. His work focuses on developing advanced nanozymes and single-atom-based catalyst systems that have the potential to revolutionize various applications in biotechnology and materials science.
Latest Patents
One of his latest patents involves RNA silencing nanozymes. These improved nanozymes are designed for targeting RNA and are synthesized using recombinant RNase A with site-specific cysteine-substituted mutations. This innovative approach allows for covalent functionalization with a length-tunable multi-thiol tether, which can be loaded onto gold particles through multiple gold-sulfur bonds. The new RNase A loading mechanism is site-specific, enabling high-density loading of alkylthiol modified DNA oligonucleotides. Additionally, these nanozymes can include extra capture strands and DNA-recombinant-RNase-A unibodies to enhance enzymatic activity and target selectivity. Another notable patent is related to single-atom-based catalyst systems, which feature total-length control of single-atom catalytic sites. This system comprises a catalyst structure with a plurality of single-atom-catalyst superparticles, allowing for controlled porosity and spatial distribution of active single-atom catalysts.
Career Highlights
Yunwei Charles Cao has worked with esteemed institutions such as the University of Florida Research Foundation and Northwestern University. His research has significantly advanced the understanding and application of nanotechnology in various fields.
Collaborations
Throughout his career, he has collaborated with notable researchers, including Rongchao Jin and Chad A Mirkin. These collaborations have further enriched his work and contributed to the development of innovative technologies.
Conclusion
Yunwei Charles Cao's contributions to the fields of nanotechnology and catalysis are noteworthy. His innovative patents and collaborations highlight his commitment to advancing scientific knowledge and technology. His work continues to inspire future innovations in these critical areas.