Location History:
- Palo Alto, CA (US) (2017 - 2019)
- Stanford, CA (US) (2019 - 2023)
Company Filing History:
4 out of 5,303 
2 out of 1,238 
Years Active: 2017-2023
Title: Innovations of Yunfeng Cheng
Introduction
Yunfeng Cheng is a prominent inventor based in Palo Alto, CA, known for his significant contributions to the field of molecular imaging and drug delivery. With a total of four patents to his name, Cheng has developed groundbreaking technologies that enhance the detection and treatment of diseases.
Latest Patents
One of his latest patents is titled "Caspase-3-triggered molecular self-assembling PET probes and uses thereof." This invention provides embodiments of the synthesis, radiolabeling, and biological applications of an activatable tracer that undergoes intramolecular cyclization and aggregation upon activation by cleavage of a blocking moiety. The probes allow for target-controlled self-assembly of small molecules in living subjects for imaging and drug delivery. The aggregated nanoprobes can be detected optically, by PET detection, magnetic resonance imaging, and other methods, depending on the detectable reporter attached to the nanoprobe. Another notable patent is for "Probes for rapid and specific detection of mycobacteria." This invention offers novel fluorogenic probes for the specific imaging and detection of mycobacteria species, particularly those resistant to β-lactam antibiotics. The specificity for mycobacteria is achieved by incorporating a moiety that targets the unique trapping mechanism of the DprE1 found in these bacteria.
Career Highlights
Yunfeng Cheng has worked at prestigious institutions, including Leland Stanford Junior University and The Texas A&M University System. His work has significantly advanced the understanding and application of molecular probes in medical diagnostics and therapeutics.
Collaborations
Cheng has collaborated with notable colleagues, including Jianghong Rao and Hexin Xie, contributing to the advancement of innovative technologies in his field.
Conclusion
Yunfeng Cheng's innovative patents and career achievements highlight his vital role in the development of advanced molecular imaging techniques and targeted drug delivery systems. His work continues to impact the medical field positively.
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