Location History:
- Hangzhou, CN (2018 - 2024)
- Zhejiang, CN (2021 - 2024)
Company Filing History:
22 out of 1,092 
3 out of 15 
2 out of 3 Years Active: 2018-2025
Title: Innovator Yuguo Zheng: Pioneering Advances in Biochemical Catalysis
Introduction
Yuguo Zheng, an accomplished inventor based in Zhejiang, China, has made significant strides in the field of biochemical catalysis. With an impressive portfolio of 17 patents, Zheng has been at the forefront of developing innovative methods for the preparation of essential compounds in pharmaceutical chemistry.
Latest Patents
Among Zheng's latest contributions is a patented method for asymmetrically preparing L-phosphinothricin through an oxidation-reduction reaction that utilizes a biological multi-enzyme coupling process. This innovative method involves catalyzing D,L-phosphinothricin with an enzyme catalysis system that includes a D-amino acid oxidase mutant and a transaminase. The novelty of this approach not only enhances catalytic efficiency but also significantly improves conversion rates compared to wild type enzymes.
Additionally, Zheng has developed a phosphinothricin dehydrogenase mutant and a recombinant bacterium, along with a one-pot multi-enzyme synchronous directed evolution method. This method allows for the efficient screening of recombinant bacteria that exhibit superior enzymatic activity. The process is characterized by a straightforward procedure, achieving up to 100% conversion of raw materials with high stereo selectivity, thus streamlining the production of L-phosphinothricin.
Career Highlights
Yuguo Zheng has collaborated with prestigious institutions like Zhejiang University and Zhejiang Chiral Medicine Chemicals Co., Ltd. During his career, he has demonstrated a commitment to advancing the understanding of enzyme catalysis and has contributed to various research projects that enhance biochemical applications in medicine and agriculture.
Collaborations
In his pursuit of scientific excellence, Zheng has worked alongside notable colleagues such as Yaping Xue and Feng Cheng. These collaborations have yielded fruitful results, driving forward the research and development of cutting-edge enzyme technologies.
Conclusion
Yuguo Zheng stands out as a prominent figure in the world of biochemical innovation. His dedication to pioneering new methods in enzyme catalysis, combined with his impressive patent portfolio, marks him as a notable inventor in the field. As he continues to push the boundaries of what's possible, Zheng's work will undoubtedly have lasting effects on pharmaceutical development and beyond.