Location History:
- Baltimore, MD (US) (1999)
- Timonium, MD (US) (1992 - 2013)
Company Filing History:
3 out of 3,687 
3 out of 676 
2 out of 190 
Years Active: 1992-2013
Title: Yuan C. Lee: Pioneering Innovations in Carbohydrate Engineering
Introduction
Yuan C. Lee, an accomplished inventor based in Timonium, MD, has made significant contributions to the field of carbohydrate engineering. With a portfolio of seven patents, he has focused on advancing methodologies that enhance the production of sialylated glycoproteins. His innovative approaches employ recombinant DNA technology and substrate feeding strategies, leading to breakthroughs in the manipulation of intracellular sialylation pathways.
Latest Patents
Among Lee's latest patents is a remarkable innovation titled "Engineering intracellular sialylation pathways." This invention provides methods for manipulating carbohydrate processing pathways in user-defined cells, facilitating the production of sialylated glycoproteins. His comprehensive approach includes the development of new carbohydrate bioassays and the investigation of selected insect cell lines. Additionally, he employs bioinformatics tools to identify gene sequences critical for processing enzymes, making these methods vital for the heterologous expression of glycoproteins.
Career Highlights
Yuan C. Lee's career is marked by invaluable contributions through his work with prestigious organizations such as The Johns Hopkins University and Human Genome Sciences, Inc. His commitment to innovation in biotechnology has established him as a key figure within the scientific community. His research endeavors have and continue to impact various applications related to recombinant protein expression and carbohydrate engineering.
Collaborations
Throughout his career, Lee has collaborated with esteemed colleagues like Michael J. Betenbaugh and Shawn M. Lawrence. These partnerships have enriched his projects and fostered a collaborative spirit that drives progress in the area of carbohydrate processing and glycoprotein development.
Conclusion
Yuan C. Lee stands at the forefront of innovations in carbohydrate engineering. His work not only contributes to the scientific community but also paves the way for advancements in therapeutic applications and biotechnology. As a prolific inventor, his contributions will undoubtedly influence future research and development in the field.