Location History:
- Iwakuni, JP (2005)
- Tsuruga, JP (1997 - 2010)
Company Filing History:
28 out of 789 
1 out of 13 
2 out of 832,912 Years Active: 1997-2010
Title: **Yoshihisa Kawamura: Innovator in Nucleotide Polymorphism and Thermostable DNA Polymerase**
Introduction
Yoshihisa Kawamura, a distinguished inventor based in Tsuruga, Japan, has made significant contributions to the field of biotechnology. With a remarkable portfolio of 31 patents, Kawamura's work primarily focuses on methods that enhance genetic analysis and polymerase chain reaction (PCR) processes.
Latest Patents
Among his latest innovations, Kawamura developed a notable patent titled "Method for Identifying Nucleotide Polymorphism." This method comprises hybridizing a labeled oligonucleotide, for a wild type or a mutant type, to a nucleic acid that contains a specific nucleotide polymorphic site in a sample. The process involves allowing a nucleic acid-specific label to act on the hybridized oligonucleotide, detecting an interaction between the labels, and identifying the nucleotide polymorphism. This identification process is based on the differential conditions experienced by the hybridized oligonucleotide.
Another significant patent is the "Modified Thermostable DNA Polymerase." In this invention, Kawamura aimed to provide a thermostable DNA polymerase that enhances both amplification efficiency and fidelity during PCR. His invention includes a specific modification within the DXE sequence and adjacent peptide regions to improve enzyme performance, enhancing the overall reliability of genetic amplification methods.
Career Highlights
Throughout his career, Kawamura has worked with prestigious companies, including Toyo Boseki Kabushiki Kaisha, where he applied his innovative skills to propel advancements in biotechnology. His dedication to research and development has positioned him as a leading figure in the field of genetic research.
Collaborations
Kawamura has collaborated with esteemed colleagues such as Bunsei Kawakami and Shinichi Teshima. These partnerships have fostered a rich environment for innovation, contributing to the advancement of scientific knowledge and application in genome analysis and biotechnology.
Conclusion
Yoshihisa Kawamura's innovative contributions to nucleotide polymorphism identification and the development of thermostable DNA polymerase highlight his essential role in advancing biotechnological methods. With 31 patents to his name, Kawamura continues to influence the landscape of genetic research, ensuring that his findings benefit scientific and medical communities worldwide.