The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2005
Filed:
Dec. 03, 2001
Takahide Kishimoto, Tsuruga, JP;
Atsushi Sogabe, Tsuruga, JP;
Shizuo Hattori, Tsuruga, JP;
Masanori Oka, Tsuruga, JP;
Yoshihisa Kawamura, Tsuruga, JP;
Takahide Kishimoto, Tsuruga, JP;
Atsushi Sogabe, Tsuruga, JP;
Shizuo Hattori, Tsuruga, JP;
Masanori Oka, Tsuruga, JP;
Yoshihisa Kawamura, Tsuruga, JP;
Toyo Boseki Kabushiki Kaisha, Osaka, JP;
Abstract
The present invention provides novel glutathione-dependent formaldehyde dehydrogenase that makes possible quantitative measurement of formaldehyde by cycling reaction, and a determination method of formaldehyde and biological components, such as creatinine, creatine, and homocysteine, which produces formaldehyde as a reaction intermediate. In addition, the present invention provides a reagent kit for the above-mentioned determination method. The present invention provides a novel determination method of a homocysteine using transferase utilizing homocysteine and other compound as a pair of substrates. Particularly, the present invention provides a determination method of homocysteine which includes bringing betaine-homocysteine methyltransferase and dimethylglycine oxidase into contact with a sample and measuring produced hydrogen peroxide or formaldehyde. Moreover, the present invention provides novel dimethylglycine oxidase stable to thiol compound, which is suitably used for the measurement. The present invention provides a reagent kit used for any of the above-mentioned determination methods of homocysteine.