Location History:
- Ecully, FR (2005)
- Palo Alto, CA (US) (2003 - 2007)
- Pearland, TX (US) (2009 - 2020)
- Gaithersburg, MD (US) (2019 - 2020)
Company Filing History:
10 out of 1,829 
6 out of 5,450 
2 out of 93 
Years Active: 2003-2020
Title: Innovations of Yong-Jun Liu in Antibody Development
Introduction
Yong-Jun Liu is a prominent inventor based in Pearland, TX (US), known for his significant contributions to the field of biotechnology. With a total of 19 patents to his name, Liu has focused on developing innovative antibodies that have the potential to transform therapeutic approaches for various diseases.
Latest Patents
Among his latest patents, Liu has developed anti-OX40 antibodies and methods of using the same. These human antibodies, which can be recombinant, humanized, or chimeric, specifically bind to the human OX40 receptor. The preferred antibodies exhibit high affinity for the OX40 receptor and are capable of activating the receptor both in vitro and in vivo. These antibodies can be utilized to modulate receptor activity in human subjects suffering from disorders where OX40 activity is detrimental. Additionally, Liu's work includes antagonistic anti-OX40L antibodies, which provide methods and compositions for treating autoimmunity and inflammatory conditions without non-specific suppression of the host immune system. These unique antibodies not only inhibit the differentiation of inflammatory T cells but also promote the generation and function of regulatory T cells, thereby enhancing therapeutic outcomes.
Career Highlights
Liu has had a distinguished career, working with notable organizations such as Schering Corporation and the University of Texas System. His experience in these institutions has allowed him to advance his research and contribute to the development of groundbreaking therapies.
Collaborations
Liu has collaborated with esteemed colleagues, including J Fernando Bazan and Kui Shin Voo, to further enhance his research and innovation in the field of antibody development.
Conclusion
Yong-Jun Liu's innovative work in the development of anti-OX40 antibodies and their applications showcases his commitment to advancing medical science. His contributions have the potential to significantly impact the treatment of autoimmune and inflammatory diseases.