The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 02, 2010

Filed:

Apr. 09, 2008
Applicants:

Gerard T. Hardiman, San Diego, CA (US);

Fernando L. Rock, La Honda, CA (US);

J. Fernando Bazan, Menlo Park, CA (US);

Robert A. Kastelein, Portola Valley, CA (US);

Stephen W. K. Ho, Palo Alto, CA (US);

Yong-jun Liu, Pearland, TX (US);

Inventors:

Gerard T. Hardiman, San Diego, CA (US);

Fernando L. Rock, La Honda, CA (US);

J. Fernando Bazan, Menlo Park, CA (US);

Robert A. Kastelein, Portola Valley, CA (US);

Stephen W. K. Ho, Palo Alto, CA (US);

Yong-Jun Liu, Pearland, TX (US);

Assignee:

Schering Corporation, Kenilworth, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C12N 15/09 (2006.01); C12P 21/06 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
Abstract

Nucleic acids encoding mammalian Toll-like receptors (TLRs) have been identified in human cells. Recombinantly produced TLRs are used in the preparation of antibodies that are capable of binding to the TLRs. The antibodies are advantageously used in the prevention and treatment of septic shock, inflammatory conditions, and viral infections.


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