Location History:
- San Jose, CA (US) (2006 - 2012)
- Freemont, CA (US) (2013)
Company Filing History:
Years Active: 2006-2013
Title: Yining Shi: Innovator in Receptor Complex Detection
Introduction
Yining Shi is a prominent inventor based in San Jose, CA, known for his significant contributions to the field of biomarker detection and cancer diagnostics. With a total of 7 patents to his name, he has made remarkable strides in understanding receptor complexes and their implications in health and disease.
Latest Patents
One of Yining Shi's latest patents focuses on "Methods for detecting receptor complexes comprising PI3K." This invention introduces a new class of biomarkers in patient samples that consist of dimers of ErbB cell surface membrane receptors. The method allows for determining the status of a disease or healthful condition by correlating it to the amounts of these dimers measured directly in patient samples, particularly in fixed tissue samples. Additionally, it provides a way to assess cancer status in specimens by measuring the presence or absence of pre-cancerous or cancerous states, prognosis, or treatment responsiveness. Another significant patent involves "Measuring receptor homodimerization," which offers methods and kits for detecting and measuring receptor homodimers on cell surface membranes. This method utilizes pairs of probes that bind specifically to the same epitope of a membrane-bound analyte, leading to the release of molecular tags that indicate the formation of homodimeric complexes.
Career Highlights
Yining Shi is currently associated with Monogram Biosciences, Inc., where he continues to innovate and develop advanced diagnostic methods. His work has been instrumental in enhancing the understanding of receptor interactions and their roles in various diseases.
Collaborations
Yining has collaborated with notable colleagues, including Sailaja Pidaparthi and Rajiv Dua, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Yining Shi's contributions to the field of biomarker detection and cancer diagnostics exemplify the impact of innovative thinking in healthcare. His patents not only advance scientific knowledge but also hold the potential to improve patient outcomes significantly.